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Xenon Pharmaceuticals Inc (XENE)

US · Healthcare · Biotechnology

$57.35+1.04%
Last close · 2026-09-17

Latest quarter · ended 2026-06-30

Revenue
$0
Net profit
$-110.7M
EPS
$-1.11
EPS estimate
$-1.16

EPS came in at -1.11 against a street estimate of -1.16 — a beat of 4.3%.

Key statistics

Market cap
$5.50B
Forward P/E
0.0
P/B
4.39
Book value
$12.84
EPS (TTM)
$-4.74
52-week high
$72.66
52-week low
$35.97
50-day MA
$63.31
200-day MA
$53.30
Beta
0.62

Analyst view

Analysts rate Xenon Pharmaceuticals Inc a strong buy (19 buy, 0 hold, 0 sell out of 19) with an average price target of $81.21.

From the latest earnings call · 2026-08-06

CONFIDENT Xenon advanced AZK NDA submission for focal seizures with best-in-class efficacy data. Expanding into depression/bipolar via Phase 3 trials, expecting MDD data H1 2027. Pain pipeline progressing with two Nav1.7/Kv7 Phase 1 programs nearing completion; added second Nav1.7 candidate. Q2 2026 U.S. focus for AZK NDA submission. X-TOLE3 includes Japanese enrollment for non-U.S. regulatory pathways. Analysts pressed on pre-NDA meeting details (resolved: productive, no agency concerns), pain safety/cardiac risk (resolved: profile comfortable for Phase 2), and general neuro adoption timing (resolved: expected sooner than typical ASM launches via service-wrapped distribution). Management confident but deferred specifics on Phase 2 pain trial design and depression efficacy thresholds. 2026-08-06…

Full summary in the app.

Shareholding

Insiders
0.11%
Institutions
107.61%

Largest institutional holders

FundStake
FMR Inc11.17%
venBio Select Advisor LLC5.97%
BlackRock Inc5.82%
Driehaus Capital Management LLC4.64%
Polar Capital Holdings PLC4.55%
HHG PLC4.31%
Capital Research & Mgmt Co - Division 32.44%
JPMorgan Chase & Co1.99%

Recent filings & reports

DocumentDate
Quarterly report · Q2 2026
XENON PHARMACEUTICALS INC. — 10-Q SUMMARY (Q2 2026) HEADLINE NUMBERS • Cash position: $119.5 million in cash and equivalents as of June 30, 2026 (do
2026-08-06
Results announced · Q3 2026
XENON PHARMACEUTICALS Q2 2026 FINANCIAL RESULTS SUMMARY HEADLINE NUMBERS • Cash, cash equivalents and marketable securities: $1,245.1 million as of
2026-08-06
Board / officer change · Q2 2026
XENON PHARMACEUTICALS INC. - 8-K SUMMARY HEADLINE NUMBERS • Annual shareholder meeting held June 2, 2026 • 90,399,636.29 common shares voted, repres
2026-06-03
Quarterly report · Q1 2026
XENON PHARMACEUTICALS INC. — FORM 10-Q SUMMARY For Quarter Ended March 31, 2026 --- HEADLINE NUMBERS • Cash & Securities Position: $1,339,621 thous
2026-05-07
Results announced · Q2 2026
XENON PHARMACEUTICALS Q1 2026 FINANCIAL RESULTS SUMMARY HEADLINE NUMBERS • Cash, cash equivalents, and marketable securities: $1,339.6 million as of
2026-05-07
Proxy statement · Q2 2026
XENON PHARMACEUTICALS INC. – PROXY STATEMENT SUMMARY WHAT SHAREHOLDERS ARE VOTING ON • Item 1: Receipt of financial statements for the year ended De
2026-04-22
Board / officer change · Q2 2026
XENON PHARMACEUTICALS INC. - 8-K SUMMARY HEADLINE NUMBERS • Stock incentive plan share pool increased by 275,000 shares (from 900,000 to 1,175,000 s
2026-04-13
Annual report FY2025
XENON PHARMACEUTICALS INC. – 10-K SUMMARY FOR RETAIL INVESTORS HEADLINE NUMBERS • Market Capitalization (June 30, 2025): $2,404.9 million (publicly
2026-02-26

Readable in the app.

Deals & corporate news

AnnouncementDate
Positive Phase 3 data reported; NDA submission planned Q3 2026
Xenon Pharmaceuticals announced positive Phase 3 results for azetukalner, its lead drug candidate for focal onset seizures (FOS). The X-TOLE2 study exceeded expectations, showing the highest
2026-05-07
Q4 2025 results; Phase 3 data milestones expected H1 2026-H1 2027
Xenon Pharmaceuticals, a biotech company developing neurological treatments, reported Q4 2025 results with strong clinical progress on its lead drug azetukalner. Key highlights: Phase 3 X-TO
2026-02-26

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Data updated 2026-09-18.