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Vertex Pharmaceuticals Inc (VRTX)

US · Healthcare · Biotechnology

$547.09+0.85%
Last close · 2026-11-06

Latest quarter · ended 2026-09-30

Revenue
$3.44B
Revenue YoY
+11.8%
Net profit
$653.6M
Profit YoY
-39.6%
EPS
$4.21
EPS estimate
$4.36
Net margin
19.0%

EPS came in at 4.21 against a street estimate of 4.36 — a miss of 3.4%.

Key statistics

Market cap
$139.16B
P/E
35.3
Forward P/E
25.1
P/B
6.64
Book value
$82.47
EPS (TTM)
$15.54
52-week high
$568.67
52-week low
$406.67
50-day MA
$522.98
200-day MA
$480.23
Beta
0.28

Analyst view

Analysts rate Vertex Pharmaceuticals Inc a buy (26 buy, 4 hold, 2 sell out of 32) with an average price target of $578.71.

From the latest earnings call · 2026-08-03

CONFIDENT Vertex posted 12% YoY revenue growth to $3.3B, raising FY26 guidance to $13.1–13.2B. CF dominance holds; CASGEVY and JOURNAVX scaling rapidly. Pove (IgAN) BLA accepted with Nov 30 PDUFA. Crinetics acquisition adds endocrine pillar. Q2 2026 CF growth balanced US/intl; ALYFTREK uptake strong in Europe (>1 in 3 eligible in Germany, UK). FX tailwind ~170 bps. Analysts pressed CF competitive bar, JOURNAVX payer dynamics, and near-term data catalysts. Management emphasized high bar for next-gen CF (must beat <30 mmol/L achievement), PSP normalization post-physician education, and upcoming AMPLIFIED/AMPLITUDE readouts (fall 2026, early 2027). 2026-08-03…

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Shareholding

Insiders
0.21%
Institutions
98.05%

Largest institutional holders

FundStake
Capital World Investors10.30%
BlackRock Inc9.51%
Capital Research Global Investors7.69%
Vanguard Capital Management, LLC6.54%
State Street Corp4.68%
Amvescap Plc.3.17%
JPMorgan Chase & Co2.57%
Geode Capital Management, LLC2.37%

Recent filings & reports

DocumentDate
Quarterly report · Q3 2026
HEADLINE NUMBERS • Third-quarter 2026 product revenue was $3,440.8 million, up from $3,076.4 million in the third quarter of 2025. • Nine-month 2026
2026-11-03
Results announced · Q4 2026
HEADLINE NUMBERS • Third-quarter 2026 revenue was $3.44 billion, up 12% from $3.0764 billion in the third quarter of 2025. • GAAP net income was $65
2026-11-02
Board / officer change · Q4 2026
OTHER NOTABLE POINTS • Vertex Pharmaceuticals appointed Daniel Brennan to its board of directors on October 20, 2026. • The board increased from ten
2026-10-20
Board / officer change · Q3 2026
VERTEX PHARMACEUTICALS INCORPORATED - FORM 8-K SUMMARY HEADLINE NUMBERS • No financial results reported in this filing (Form 8-K is a personnel/gove
2026-09-01
Quarterly report · Q2 2026
VERTEX PHARMACEUTICALS INCORPORATED Q2 2026 10-Q SUMMARY FOR RETAIL INVESTORS --- HEADLINE NUMBERS • Total revenues (6 months ended June 30, 2026):
2026-08-04
Results announced · Q3 2026
VERTEX PHARMACEUTICALS Q2 2026 FINANCIAL SUMMARY HEADLINE NUMBERS • Total revenue: $3.33 billion in Q2 2026, up 12% from Q2 2025 • Full-year 2026 re
2026-08-03
Material agreement · Q3 2026
VERTEX PHARMACEUTICALS ACQUISITION OF CRINETICS PHARMACEUTICALS HEADLINE NUMBERS • Vertex Pharmaceuticals agreed to acquire Crinetics Pharmaceutical
2026-07-07
Board / officer change · Q2 2026
VERTEX PHARMACEUTICALS INCORPORATED - 8-K SUMMARY BUSINESS & SEGMENT HIGHLIGHTS • This is a corporate governance filing related to the company's ann
2026-05-13

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Deals & corporate news

AnnouncementDate
Full-year revenue guidance raised to $13.15 billion–$13.25 billion
Vertex reported strong third-quarter operating performance, but acquisition costs significantly reduced GAAP earnings. Revenue rose 12% year over year to $3.44 billion, helped by continued d
2026-11-02
Entered into agreement to acquire Crinetics Pharmaceuticals
Vertex Pharmaceuticals reported strong Q2 2026 results with total revenue of $3.33 billion, up 12% year-over-year. The company raised its full-year 2026 revenue guidance to $13.1-$13.2 billi
2026-08-03
Execution of merger agreement with Parent announced
On July 6, 2026, a company announced it signed a merger agreement to be acquired by a parent company. The deal is expected to bring significant benefits: the combined entity could generate o
2026-07-07
Full year 2026 revenue guidance provided; non-CF products expected to contribute $500M+
Vertex Pharmaceuticals reported strong 2025 financial results with $12.0 billion in total revenue, a 9% increase year-over-year. Fourth quarter revenue reached $3.19 billion, up 10% from the
2026-02-12

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Data updated 2026-11-07.