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USHealthcare

Stoke Therapeutics Inc (STOK)

US · Healthcare · Biotechnology

$28.93+3.65%
Last close · 2026-09-17

Latest quarter · ended 2026-06-30

Revenue
$9.3M
Revenue YoY
-32.5%
Net profit
$-61.6M
EPS
$-0.93
EPS estimate
$-0.82
Net margin
-660.8%

EPS came in at -0.93 against a street estimate of -0.82 — a miss of 13.4%.

Key statistics

Market cap
$1.80B
Forward P/E
204.1
P/B
5.26
Book value
$5.54
EPS (TTM)
$-3.36
52-week high
$40.22
52-week low
$20.32
50-day MA
$30.78
200-day MA
$31.97
Beta
1.23

Analyst view

Analysts rate Stoke Therapeutics Inc a strong buy (9 buy, 1 hold, 0 sell out of 10) with an average price target of $46.46.

From the latest earnings call · 2026-08-03

CONFIDENT EMPEROR Phase III enrollment complete (162 patients, 0 discontinuations). Data readout Q3 2027 supports NDA filing Q1 2027. $420M cash runway to early 2028 launch. OLE data show durable seizure reduction and cognitive gains through 4 years. Q2 2026 U.S. is primary focus with 16,000-patient prevalence. Europe supports EMPEROR completion. Biogen handles ROW expansion. Analysts probed study powering (2–3 point Vineland delta vs. 8–11 observed), disease-modification label narrative (OLE data inclusion strategy), and commercial capacity (SPINRAZA precedent). Management emphasized 0% discontinuation dramatically improves secondary endpoint power, FDA pre-NDA meeting to align on OLE inclusion and SAP hierarchy, and site readiness via existing intrathecal infrastructure. 2026-08-03…

Full summary in the app.

Shareholding

Insiders
3.68%
Institutions
123.61%

Largest institutional holders

FundStake
RTW INVESTMENTS, LLC8.72%
BlackRock Inc8.35%
FMR Inc8.34%
Lynx1 Capital Management, LP6.26%
Redmile Group, LLC6.12%
Wellington Management Company LLP5.45%
Morgan Stanley - Brokerage Accounts5.31%
Baker Bros Advisors LP5.17%

Recent filings & reports

DocumentDate
Quarterly report · Q2 2026
STOKE THERAPEUTICS, INC. – Q2 2026 10-Q SUMMARY HEADLINE NUMBERS • Cash & Equivalents: $110.0 million as of June 30, 2026 (up from $84.2 million Dec
2026-08-03
Company announcement · Q3 2026
STOKE THERAPEUTICS, INC. - 8-K FILING SUMMARY HEADLINE NUMBERS • Company filed prospectus supplement on August 3, 2026 for up to $200,000,000 in new
2026-08-03
Results announced · Q3 2026
STOKE THERAPEUTICS Q2 2026 FINANCIAL RESULTS SUMMARY HEADLINE NUMBERS • Cash position: $420.0 million (comprised of $354.3 million as of June 30, 20
2026-08-03
Reg FD disclosure · Q2 2026
STOKE THERAPEUTICS, INC. – 8-K SUMMARY (June 30, 2026) HEADLINE NUMBERS • Phase 3 EMPEROR study enrollment complete: 162 patients enrolled across U.
2026-06-30
Shareholder vote results · Q2 2026
STOKE THERAPEUTICS, INC. - 8-K SUMMARY HEADLINE NUMBERS • Annual stockholder meeting held June 3, 2026 • Three Class I directors elected to three-ye
2026-06-04
Quarterly report · Q1 2026
STOKE THERAPEUTICS, INC. – 10-Q SUMMARY (Q1 2026) HEADLINE NUMBERS • Cash position: $155.7 million in cash and cash equivalents as of March 31, 2026
2026-05-07
Proxy statement · Q2 2026
STOKE THERAPEUTICS, INC. – PROXY STATEMENT SUMMARY --- CEO COMPENSATION AND CHANGE • Ian F. Smith's total compensation: Document does not specify e
2026-04-22
Annual report FY2025
STOKE THERAPEUTICS, INC. — 10-K SUMMARY FOR RETAIL INVESTORS HEADLINE NUMBERS • Public company: Stoke Therapeutics, Inc. (Ticker: STOK, Nasdaq) • Fi
2026-03-16

Readable in the app.

Deals & corporate news

AnnouncementDate
Lease agreement for new facility or production space
Stoke Therapeutics filed an 8-K on January 27, 2026, disclosing a lease agreement. Item 2.03 of the filing references Item 1.01, which contains details about the lease arrangement. However,
2026-01-26

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Data updated 2026-09-18.