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Krystal Biotech Inc (KRYS)

US · Healthcare · Biotechnology

$338.75+0.62%
Last close · 2026-09-17

Latest quarter · ended 2026-06-30

Revenue
$119.2M
Revenue YoY
+24.1%
Net profit
$54.8M
Profit YoY
+42.9%
EPS
$1.79
EPS estimate
$1.70
Net margin
45.9%

EPS came in at 1.79 against a street estimate of 1.70 — a beat of 5.3%.

Key statistics

Market cap
$10.23B
P/E
43.3
Forward P/E
47.4
P/B
7.52
Book value
$45.92
EPS (TTM)
$7.98
52-week high
$382.54
52-week low
$145.46
50-day MA
$348.21
200-day MA
$292.48
Beta
0.54

Analyst view

Analysts rate Krystal Biotech Inc a strong buy (10 buy, 1 hold, 0 sell out of 11) with an average price target of $385.00.

From the latest earnings call · 2026-08-03

CONFIDENT VYJUVEK revenue hit $119.2M (+24% YoY) driven by U.S. strength ($91.6M) and early European launches. Pipeline advancing: two ocular registrational readouts imminent, CF and Haley-Haley moving to 2027 trials, KB707 oncology progressing. Germany pricing negotiations ongoing with Q3 resolution expected. Q2 2026 U.S. drove 77% of Q2 revenue. European launches navigating country-specific access dynamics (GMO classification in France, fragmented care in Germany, prescription renewal burden in Japan). Germany pricing negotiations expected to resolve Q3, releasing accrual headwind. Analysts pressed on German pricing accrual impact and European demand durability; management clarified strong underlying vial/patient growth masking near-term reserve headwinds. NK global enrollment and readout timing questioned; management confirmed year-end enrollment, early 2027 data, and EU site activati…

Full summary in the app.

Shareholding

Insiders
10.66%
Institutions
102.40%

Largest institutional holders

FundStake
FMR Inc14.78%
BlackRock Inc13.31%
venBio Select Advisor LLC9.76%
Vanguard Portfolio Management, LLC4.92%
State Street Corp4.44%
Vanguard Capital Management, LLC3.94%
Soleus Capital Management, L.P.3.17%
Capital World Investors2.63%

Recent filings & reports

DocumentDate
Quarterly report · Q2 2026
KRYSTAL BIOTECH, INC. - Q2 2026 10-Q SUMMARY HEADLINE NUMBERS • Product Revenue (6 months): $235.6 million vs. $184.2 million prior year (+28% YoY)
2026-08-03
Results announced · Q3 2026
KRYSTAL BIOTECH Q2 2026 FINANCIAL SUMMARY HEADLINE NUMBERS • Q2 2026 VYJUVEK product revenue: $119.2 million, up 24% versus Q2 2025 ($96.0 million)
2026-08-03
Company announcement · Q3 2026
KRYSTAL BIOTECH, INC. – FORM 8-K SUMMARY HEADLINE NUMBERS • No financial metrics provided in this disclosure (Form 8-K is an event-based filing, not
2026-07-21
Shareholder vote results · Q2 2026
KRYSTAL BIOTECH, INC. - FORM 8-K SUMMARY HEADLINE NUMBERS • Annual Meeting of Stockholders held May 15, 2026 • Company trades as KRYS on Nasdaq Glob
2026-05-20
Quarterly report · Q1 2026
KRYSTAL BIOTECH, INC. – Q1 2026 10-Q SUMMARY HEADLINE NUMBERS • Product Revenue Q1 2026: $116.4 million (vs. $88.2 million Q1 2025) – increase of 32
2026-05-04
Current report · Q2 2026
KRYSTAL BIOTECH, INC. - FORM 8-K SUMMARY HEADLINE NUMBERS • Company announced Q1 2026 financial results on May 4, 2026 • Stock trades on Nasdaq Glob
2026-05-04
Proxy statement · Q2 2026
KRYSTAL BIOTECH, INC. - PROXY STATEMENT SUMMARY CEO COMPENSATION & CHANGE • CEO Total Compensation: The document does not provide specific numerical
2026-04-03
Annual report FY2025
KRYSTAL BIOTECH, INC. – 2025 10-K SUMMARY HEADLINE NUMBERS • Market value of common stock held by non-affiliates (as of June 30, 2025): $3.5 billion
2026-02-17

Readable in the app.

Deals & corporate news

AnnouncementDate
2025 revenue and 2026 expense guidance provided ahead of healthcare conference
Krystal Biotech announced preliminary 2025 financial results for its gene therapy product VYJUVEK ahead of the J.P. Morgan Healthcare Conference. Key numbers: VYJUVEK generated $106-107 mill
2026-01-12
Commercial launch of VYJUVEK in Japan following NHI pricing approval
Krystal Biotech announced that its Japanese subsidiary began commercial sales of VYJUVEK (beremagene geperpavec) on October 22, 2025, following approval for Japan's National Health Insurance
2025-10-22

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Data updated 2026-09-18.