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USHealthcare

BioCryst Pharmaceuticals Inc (BCRX)

US · Healthcare · Drug Manufacturers - Specialty & Generic

$8.70+3.20%
Last close · 2026-09-17

Latest quarter · ended 2026-06-30

Revenue
$218.2M
Revenue YoY
+33.6%
Net profit
$78.4M
Profit YoY
+1441.7%
EPS
$0.30
EPS estimate
$0.14
Net margin
35.9%

EPS came in at 0.30 against a street estimate of 0.14 — a beat of 114.3%.

Key statistics

Market cap
$2.12B
Forward P/E
14.9
P/B
56.59
Book value
$-1.78
EPS (TTM)
$-1.32
52-week high
$11.22
52-week low
$6.00
50-day MA
$9.68
200-day MA
$8.60
Beta
0.56

Analyst view

Analysts rate BioCryst Pharmaceuticals Inc a buy (11 buy, 1 hold, 0 sell out of 12) with an average price target of $20.64.

From the latest earnings call · 2026-08-05

CONFIDENT BioCryst delivered strong Q2 with ORLADEYO growing 10% YoY, pediatric launch off to robust start (47 Rx vs. full-year expectations), and navenibart enrollment complete ahead of schedule. Cost cuts underway post-Birmingham closure. Q2 2026 Navenibart EU rights licensed to Neopharmed Gentili. Former European ORLADEYO business divested. U.S. focus for ORLADEYO growth. Analysts pressed on ORLADEYO volume breakdown (Charlie clarified 50/50 split), Netherton efficacy bar (Sandeep: first targeted KLK5 therapy; any relief major advance), and pediatric paid rates (Charlie: expect 80%+; early signs strong). Management confidence throughout; no material walk-backs. 2026-08-05…

Full summary in the app.

Shareholding

Insiders
1.20%
Institutions
105.38%

Largest institutional holders

FundStake
BlackRock Inc8.86%
RA Capital Management, LLC6.19%
Deerfield Management Co5.88%
State Street Corp4.78%
Vanguard Portfolio Management, LLC4.40%
Vanguard Capital Management, LLC4.36%
TCG Crossover Management, LLC4.31%
HHG PLC3.49%

Recent filings & reports

DocumentDate
Quarterly report · Q2 2026
BIOCRYST PHARMACEUTICALS, INC. — Q2 2026 10-Q SUMMARY HEADLINE NUMBERS • Cash and equivalents: $154.972 million (June 30, 2026) vs $89.736 million (
2026-08-05
Results announced · Q3 2026
BIOCRYST PHARMACEUTICALS Q2 2026 FINANCIAL SUMMARY HEADLINE NUMBERS • Q2 2026 Total Revenue: $218.3 million (+34% year-over-year; +45% excluding Eur
2026-08-05
Reg FD disclosure · Q2 2026
BIOCRYST PHARMACEUTICALS, INC. - FORM 8-K SUMMARY HEADLINE NUMBERS • Report Date: June 25, 2026 (Board approval); June 29, 2026 (public announcement
2026-06-29
Board / officer change · Q2 2026
BIOCRYST PHARMACEUTICALS, INC. — FORM 8-K SUMMARY HEADLINE NUMBERS • Annual Meeting held June 11, 2026 • 7,000,000 additional shares approved for is
2026-06-12
Quarterly report · Q1 2026
BIOCRYST PHARMACEUTICALS, INC. — Q1 2026 SUMMARY HEADLINE NUMBERS • Cash position: $171.6 million in cash and cash equivalents as of March 31, 2026
2026-05-06
Results announced · Q2 2026
BIOCRYST PHARMACEUTICALS Q1 2026 FINANCIAL SUMMARY HEADLINE NUMBERS • Q1 2026 ORLADEYO net revenue: $148.3 million (+11% year-over-year; +21% exclud
2026-05-06
Proxy statement · Q2 2026
BIOCRYST PHARMACEUTICALS, INC. – PROXY STATEMENT SUMMARY --- WHAT SHAREHOLDERS ARE VOTING ON • Proposal 1: Election of Three Directors – Voting to
2026-04-23
Annual report FY2025
BIOCRYST PHARMACEUTICALS, INC. – 10-K SUMMARY FOR RETAIL INVESTORS HEADLINE NUMBERS • Market Capitalization: $1.86 billion (as of June 30, 2025, bas
2026-02-26

Readable in the app.

Deals & corporate news

AnnouncementDate
Maintained ORLADEYO revenue guidance, increased total revenue guidance for 2026
BioCryst Pharmaceuticals reported strong Q2 2026 results with total revenue of $218.3 million (up 34% year-over-year) and ORLADEYO net revenue of $158.2 million. The company achieved operati
2026-08-05
2026 non-GAAP operating expense guidance improved; revenue guidance reaffirmed
BioCryst Pharmaceuticals announced a strategic shift to focus on external innovation rather than internal drug discovery. The company will close its Birmingham, Alabama research facility by
2026-06-29
Licensing agreement for European navenibart rights to Neopharmed Gentili
BioCryst Pharmaceuticals reported strong Q1 2026 results with ORLADEYO (its main drug for hereditary angioedema) generating $148.3 million in revenue, up 11% year-over-year. More importantly
2026-05-06
European licensing agreement for navenibart in hereditary angioedema
BioCryst Pharmaceuticals signed a licensing deal with an Irish affiliate of Neopharmed Gentili to commercialize navenibart (an experimental HAE treatment) in Europe. BioCryst will receive $7
2026-05-04
Completed acquisition of Astria Therapeutics to expand HAE portfolio
BioCryst Pharmaceuticals achieved a major milestone in 2025 by reaching full-year profitability for the first time in company history. Their flagship drug ORLADEYO generated $601.8 million i
2026-02-26

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Data updated 2026-09-18.